" Home Tools. Repeat dose in 10 days : Anthelminthic: Piperazine citrate: 100mg/kg/day for 2 doses : 200mg/kg orally: 200mg/kg orally: Anthelminthic. Piperazine adipate (10 mM) also inhibits cholinesterase activity by 96% in Ascaridia galli (A. galli) and 93% in Heterakis gallinae (H. gallinae). Molecular Formula. Log in . For tablet dosage form: For common roundworms: Adults and teenagers3.5 grams (piperazine hexahydrate) per day for two days in a row. Piperazine for Cats Overview. Treatment needs to be repeated in 7-10 days since the drug does not kill the large . Piperazine adipate oral suspension: For treating roundworm or pinworm infections: The recommended oral dose for Adult and children above 14 years is 1.8g orally for every 4 hours three times a day . Piperazine has a high therapeutic index with LD 50 values of more than 4000 mg/kg in mice for both the hexahydrate and adipate salts (Cross et al., 1954). Doses . If given by mouth: 50 mg/bird (if younger than 6 weeks of age), otherwise 100 mg/bird (if older than 6 weeks of age), or according to the manufacturer label. 142-88-1) is an alternative treatment for ascariasis caused by roundworms and Oxyuriasis by pinworms.With the Molecular Formula of C 10 H 20 N 2 O 4,it is especially useful in the treatment of partial intestinal obstruction caused by Acaris worms, which is commonly seen . This type of drug functions by targeting the nervous systems of the parasites that are attached to your cat's intestinal wall. While . Grow Your Pharma Business Digitally. Compounds of the formula II: wherein R1 and R2 are independently H, F or CH3; or R1 forms an ethynyl bond and R2 is H or C3-C6 cycloalkyl which is optionally substituted with one or two substituents independently selected from methyl, CF3, OMe or halo; R3 is C1-C3 alkyl or C3-C6 cycloalkyl, either of which is optionally substituted with one or two methyl and/or a fluoro, trifluoromethyl or . Piperazine is freely soluble in water and ethylene glycol, but insoluble in diethyl ether. Anthelminthic . Access now . Formula C10H20N2O4 Molecular Weight 232.277 Exact Mass 232.142 LogP 0.5528 PSA 98.66 Synonyms PIPERAZINE . General Description. dosage, form, labeller, route of administration, and marketing period. The amount of anthelmintic base in active piperazine salts is respectively, for adipate 37%, chloride 48%, citrate 35%, dihydrochloride 50 to 53%, hexahydrate 44%, phosphate 42% and sulphate 46%. List of Drug Master Files (DMF) of Piperazine Adipate Active Pharmaceutical Ingredient (API) submitted to the U.S. FDA. WARNINGS: Do not worm a kitten less than six weeks of age. The main component of this drug is called piperazine adipate, so you can find a similar drug on sale, called that way. Slightly acid taste. Piperazine is a narrow-spectrum anthelmintic effective maily against gastrointestinal ascarids. Contact. H2O: 14.29 mg/mL (61.52 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble ) Citations. Sharma R K , Singh K , Saxena K K .

Presentation Creator Create stunning presentation online in just 3 steps. Inhibitor Targets. CAS No. Repeat dose in 10 days. ADAPALENE Powder Get latest price ALBUTEROL SULPHATE Get latest price Acenocoumarol Powder Get latest price Aceclofenac Get latest price. Pure piperazine itself is unstable in water and to ensure the required stability in human and veterinary medicines various salts are used (e.g. In some cases, particularly for aceclidine, stability in solution is . Piperazine adipate: .5g/kg/day for 2 doses: 500 micrograms/kg/day. Schistosomiasis. When this is taken into account, the results of the present study support those of earlier workers i.e.

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Sodium Citrate Dehydrate Powder, Povidone Iodine Powder, Piperazine Adipate Powder, Potassium Magnesium Citrate Powder, Oxyclozanide Powder, etc. Pro Get powerful tools for managing your contents. Effect of parbendazole and piperazine . Piperazine readily absorbs water and carbon dioxide from the air. Piperazine adipate -25 gram Pharmacological properties : Fenbendazole (5-phenylthio-2-benzimidazole carbamate) has a wide range of nematodicidal, cestodocidal action, is active against adult forms and larvae of nematodes of the gastrointestinal tract and lungs and certain types of trematodes and cestodes. For animals under 5 pounds (2.5 kg), the maximum dose should not exceed 150 mg. Be certain to give this medicine in the manner advised by your veterinarian. Piperazine Adipate is A white or almost white Crystalline Powder. Create. Ahmedabad . Jigs Chemical Limited. The oral LD50 of piperazine adipate in mice is 11.4 g/kg. Collection of Piperazine adipate slideshows. In between cycles, it is recommended to do an enema at night to remove pinworms from the rectum - for adults 4-5 glasses of water, children - 1-3 glasses of water with the addition 0,5 teaspoons of sodium bicarbonate in a glass of water. Find Piperazine Adipate Oral Powder exporters, adipate . It is a weak base with two pK b of 5.35 and 9.73 at 25 C. C10H20N2O4. Get best price and read about company. The piperazine salts are used for the treatment of ascarids in dogs, cats, horses, pigs and poultry.Piperazine Kyron is a white crystalline powder consisting of I 00% piperazine adipate (=37% piperazine base).Piperazine acts by altering muscular polarisation in susceptible nematodes, thereby paralysing the worm and allowing it to be passed out with the faeces. HHS Vulnerability Disclosure. US EN. The tablets themselves are round, white, and are at risk of being split into halves. Piperazine is an antihelminthic drug that selectively blocks the neuromuscular cholinergic receptors of worms. Sloan et al. Login; Upload 'Piperazine adipate' presentation slideshows. Of the auxiliary substances in "Piperazine" there are potato or corn starch and . Treatment may need to be repeated in one week. hexahydrate, phosphate and adipate) are given as water soluble powder or as solutions mostly mixed into water or animal feed. Used to treat cestodes: Prednisone Solubility Information. It is readily absorbed, but has a highly variable half-life. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6. Adults and teenagers3.5 grams (piperazine hexahydrate) per day for two days in a row. Treatment may need to be repeated in one week. 8,562/ PIECE Get Latest Price. PHYSICAL DESCRIPTION: Odorless white crystalline powder or solid. with piperazine (1:1) . Access now. Expired - Lifetime Application number US463317A Inventor Forrest James Petrow Vladimir Current Assignee (The listed . Derivatives of piperazine are widely used in the pharmaceutical, biomedical and chemical fields. National Institutes of Health. If added to flock water .

Praziquantel: 5.1-11.4mg/kg orally, SC or IM . All Photos (1) P1900000. Get contact details, email, phone and address of companies manufacturing and supplying Piperazine Adipate Oral Powder along with details of Piperazine Adipate Oral Powder importers and buyers. Dosage depends on the geographical origin of the in-fection and total doses range from 15 mg/kg as a single dose to 60 mg/kg given over 2 to 3 days. 8600 Rockville Pike, Bethesda, MD, 20894 USA. The medicine is presented in pharmacies in two dosages - 200 mg or 500 mg of the active compound in one tablet. PowerPoint Templates.

The posology depends on the animal species, and also on the salt used. Piperazine . 3mg/ml in drinking water orally: 200mg/kg orally for 7 days (for pinworm) Anthelminthic. Recent Presentations Content Topics Updated Contents Featured Contents. Piperazine Adipate Oral Powder, Get suppliers, exporters, manufacturers and buyers of Piperazine Adipate Oral Powder in India and overseas. Piperazine Adipate exists as small alkaline deliquescent crystals with a saline taste. Price Inquiry . 232.28. Treatment needs to be repeated in 7-10 days since the drug does not kill the large roundworm eggs. However, the usual dose is 65 mg (piperazine hexahydrate) per kilogram (29.5 mg per pound) of body weight per day for seven days in a row. 1- (2-Methoxyphenyl)Piperazine Hydrobromide CAS 100939-96-6 CAS: 100939-96-6 Molecular Formula: C11H17BrN2O Quality Standard: pharm grade Packing: 25kg/fiber drum Mininmum Order: 25kg. It especially affects immature and sexually mature individuals of helminths of both sexes (roundworms and pinworms), causing muscle paralysis of these nematodes. Piperazine adipate (10 mM) causes mortality of A. galli and H. gallinae after a maximum of 30 min exposure, inhibits malate oxidation by 78%, and inhibits aldolase activity in both parasites. PharmaCompass' API Reference Price for Piperazine Adipate determined using sample data obtained from Indian Trade (Import/Export). Powder: -20C for 3 years. Get here the data of piperazine adipate (cas no 142-88-1), piperazine adipate manufacturers, suppliers and exporters. Used to treat ascarids and some nodular worms and pin worms. Policies. Piperazine adipate is an insoluble salt.18 It is stable to heat and 494. Effects of Punica granatum Fruit Dry Rind Powder and Piperazine Adipate against Ascaridia galli. The range of quality piperazine adipate offered by Indian manufacturing companies are high in demand. Antiparasitic. (1954), Shumard and Eveleth (1955), Horton-Smith and Kids can assign ready 5% solution. In dogs and cats, piperazine is dosed at 25 to 50 mg per pound (50 to 110 mg/kg). Product name : Piperazine adipate Catalog No. It causes the worms to become paralyzed, which forces them to detach from the intestinal wall and allows your cat's body to flush them out through normal excretory processes. Missed dose If you miss a dose of piperazine, take it as soon as possible. Dosage: Calulate dose rate of 4mL per 5kg bodyweight. Repeat dose in 10 days. In the last one year, MRP increase has been only 9% in all varieties except full cream where it is 12% to 13% vis--vis price paid to the farmers have increased by 15%. Estimated API Price per kg in USD for Piperazine Adipate obtained from the import, export data from major ports of India . Original Data : FDA Website The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in . 142-88-1 Piperazine adipate Assay:99% Appearance:White fine powder Package:according to the clients requirement Storage:Store in dry dark and ventilated place Transportation:Transportation by express, air, sea; port mainly to Qingdao / Tianjin / Shanghai, or according to customer needs to send different ports and aviation.Application:It is an important raw material. Piperazine is a type of drug called an anthelmintic. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Applications Products Services Support.

However, the usual dose is 75 mg (piperazine hexahydrate) per kilogram (34 mg per pound) of body weight per day for two days in a row. : 142-88-1 | CAS NO. Piperazine | C4H10N2 | CID 4837 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Other muscarinic agonists with a quinuclidine ring include but are not limited to cevimeline, talsaclidine, and WAY-132983. Piperazine is the only FDA approved dewormer for use in laying hens in the United States. This is equivalent to 32 mg piperazine per kg bodyweight Cattle, horses, pigs : 2,2 g Piper Dewormer wsp per 10 kg bodyweight, equivalent to 110 mg of piperazine base per kg bodyweight. 1- (2-Methoxyphenyl)Piperazine Hydrobromide CAS 100939-96-6. Piperazine adipate (10 mM) also inhibits cholinesterase activity by 96% in Ascaridia galli (A. galli) and 93% in Heterakis gallinae (H. gallinae). [0001] Aceclidine is a muscarinic agonist with a quinuclidine ring (a tertiary nitrogen as part of a heterocyclic carbon ring) along with an acetyl ester bond to the heterocyclic ring two carbons away. read more. Animals with known kidney pathology should be treated only . Product Ingredients . 1.

It has Molecular formula CC4H10N2,C6H10O4, Molecular weight 232.3g/mol. Website Search Google Search Access drug product information from over 10 global regions. : 142-88-1 | Brand: BOC Sciences. It has no effect on any other species of worms, including tapeworms. X. PHARMA COMPASS.

: HY-B2186 CAS No. Dissolves slowly. ; the pH of a 10% aqueous solution of piperazine is 10.8-11.8. Get latest price. In Vitro. Manufacturer of Piperazine Derivatives - Piperazine Citrate, Piperazine Adipate offered by Adani Pharmachem Private Limited, Rajkot, Gujarat. Please Wait. Piperazine Adipate is used as an anthelmintic agent. Applying Filters. Piperazine Adipate(CAS NO. Piperazine adipate: 200 mg/kg PO q24h 7 days, off 7 days, on 7 days 3: Rats/pinworms : 200-600 mg/kg PO q24h 7 days, off 7 days, on 7 days 3: Gerbils : 500 mg/kg PO q24h 66: Chinchillas : 0.5 mg/mL drinking water 21 days 3: Rats/pinworms : 3-5 mg/mL drinking water 7 days, off 7 days, on 7 days 66: Hamsters : 4-7 mg/mL drinking water .

Cautions. January 2007; Saudi Journal of Biological Sciences 14(2):185-192; Authors: Areej O. Bakraibah . Piperazine can be given orally by mouth in each bird, or added to the flock's water source. All Photos (1) Empirical Formula (Hill Notation): C . The adult oral dose of 4 g of piperazine hydrate has been used extensively in the treatment of ascariasis. Novel oxadiazole derivatives of the formula (I), in which R, R, Y, X 1, X 2 and X 3 have the meanings indicated in claim 1, are kinase inhibitors and can be used for the treatment of diseases and conditions such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and kidney diseases, in general in all types of fibroses .

Synonym: Piperazine adipate; NSC 74383; NSC-74383; NSC74383; IUPAC/Chemical Name: Hexanedioic acid, compd. Find list of most trusted exporters of Piperazine Adipate Oral Powder in India with contact details including address, email and phone number. hydrate, citrate, adipate, phosphate, etc.). 0 Call Us +918071858930886 Send Inquiry The leading GMP & ISO Approved Piperazine manufacturer in India provides you with the best quality Piperazine Adipate Manufacturer Exporter in India. This dose may need to be repeated in 21 days. Post Enquiry. Drugs . This dosage is based on layers with a bodyweight of 2,5 kg and a water uptake of 210 ml per animal per day. Its holds from 98.0% to 101.0% Assay on dry basis. Each salt contains a different amount of piperazine "base": adipate 37%; chloride 48%; citrate 35%; phosphate 42%; the hexahydrate 44%, the sulphate 46%. Piperazine is a medication used to treat roundworm and pinworm. Vishal Laboratories - Offering Piperazine Adipate IP, Piperazine Adipate in Rajkot, Gujarat. ChildrenDose is based on body weight and must be determined by your doctor. Although many piperazine derivatives occur naturally, piperazine . PIPERAZINE ADIPATE V7P5P122LB US Previously Marketed Source: PIPERAZINE CITRATE by ALPHARMA US PHARMS (1982) Source URL: . The 'Hazard classification and labelling' section shows the hazards of a substance through a standardised system of statements and pictograms, as has been established under CLP (Classification Labelling and Packaging) Regulation. FOIA. References and Literature. Piperazine Adipate is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. If you compare the input cost increase, dry fodder cost has increased by more than 60-70%, green fodder by 40-50% and cattle feed price has increased by 20-22%. Molecular Weight. Online. Doses expressed in terms of the amount of piperazine base are: for swine 110 mg/kg bw and for poultry 32 mg/kg bw . Anthelminthic . Piperazine Adipate: Sigma-Aldrich: For experimental / research use only.

Piperazine adipate. Piperazine derivatives are known to have high antiserotonin potency, antimicrobial activity, and potential anticancer activity in humans. Required fields are marked with * Services & Products of Interest * Project Description . Appearance: Solid powder Purity: >98% (or refer to the Certificate of Analysis) Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. Category. It is only effective against the adult large roundworm. Repeat in 7-10 days. Such side effects are usually associated with over-dosage. Oxamniquine is an alternative to praziquan- tel for the treatment of schistosomiasis (p.138) due to Schisto-soma mansoni, although resistance has occurred, particularly in South America,1 . Presentation Survey Quiz Lead-form E-Book. CAS number:18428-63-2 (18833-13-1)Certificate: ISO CERTIFICATE, FACTORY GMP, Properties : Synonym 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7h-purine- More. Adults and childrenDose is based on body weight and must be determined by your doctor. Hazard classification and labelling. Catalog NO. Piperazine Adipate Original . The corres-ponding figures for adipate and citrate are 37% and 35% respectively. June 13-16, 2022 Booth 1441.